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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC4A1
All Species:
3.64
Human Site:
S350
Identified Species:
10
UniProt:
P02730
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02730
NP_000333.1
911
101792
S350
L
R
R
R
Y
Q
S
S
P
A
K
P
D
S
S
Chimpanzee
Pan troglodytes
XP_511548
900
100325
C317
L
A
G
A
V
G
A
C
K
I
S
P
T
P
S
Rhesus Macaque
Macaca mulatta
XP_001103478
1172
130022
G572
L
K
K
R
E
E
Q
G
R
L
L
P
T
G
A
Dog
Lupus familis
XP_532761
1223
134633
G636
L
K
K
R
E
E
Q
G
R
L
L
P
P
G
A
Cat
Felis silvestris
Mouse
Mus musculus
P04919
929
103117
S363
L
R
R
R
Y
L
P
S
P
A
K
P
D
P
N
Rat
Rattus norvegicus
P23562
927
103154
R363
L
R
K
R
Y
L
P
R
P
A
K
P
D
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P15575
922
102205
P357
V
R
R
R
Y
Q
H
P
D
T
V
R
S
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107912
1232
137883
G640
L
R
K
R
E
E
Q
G
V
A
L
M
A
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791964
1247
140119
L634
K
K
M
R
A
E
T
L
A
E
E
A
D
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
49.3
45.7
N.A.
81.3
81.4
N.A.
N.A.
61.8
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
36.4
Protein Similarity:
100
93
62.8
58.5
N.A.
88.1
89.2
N.A.
N.A.
74.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
100
20
20
20
N.A.
73.3
60
N.A.
N.A.
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
46.6
46.6
N.A.
80
73.3
N.A.
N.A.
40
N.A.
40
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
12
12
0
12
0
12
45
0
12
12
0
23
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
45
0
12
% D
% Glu:
0
0
0
0
34
45
0
0
0
12
12
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
12
0
34
0
0
0
0
0
34
12
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
12
34
45
0
0
0
0
0
12
0
34
0
0
12
0
% K
% Leu:
78
0
0
0
0
23
0
12
0
23
34
0
0
0
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% N
% Pro:
0
0
0
0
0
0
23
12
34
0
0
67
12
45
0
% P
% Gln:
0
0
0
0
0
23
34
0
0
0
0
0
0
0
0
% Q
% Arg:
0
56
34
89
0
0
0
12
23
0
0
12
0
0
0
% R
% Ser:
0
0
0
0
0
0
12
23
0
0
12
0
12
12
23
% S
% Thr:
0
0
0
0
0
0
12
0
0
12
0
0
23
0
0
% T
% Val:
12
0
0
0
12
0
0
0
12
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _